Objective: To assess the adequacy of the process of informed consent for surgical patients at the University Hospital of the West Indies. Method: The study is a prospective, cross-sectional, descriptive study. 210 patients at the University Hospital of the West Indies were interviewed using a standardised investigator-administered questionnaire, developed by the authors, after obtaining witnessed, informed consent for participation in the study. Data were analysed using SPSS V.12 for Windows. Results: Of the patients, 39.4% were male. Of the surgical procedures, (...) 68.6% were scheduled, 7.6% urgent and 23.8% emergency, 35.2% were minor and 64.8% major. Information imparted/received was acceptable in 40% of cases, good in 24% and inadequate (unacceptable) in 36% of cases. Almost all (97.6%) patients stated that they understood why an operation was planned and 93.3% thought that they had given informed consent. Most (95.2%) thought that they had free choice and made up their own mind. A quarter (25.2%) of all patients were told that it was mandatory for them to sign the form. There was a discussion of possible side effects and complications in 56.7% of patients. Conclusions: This study clearly indicates that surgical patients at the University Hospital of the West Indies feel that they have given informed consent. However, it also suggests that more information should be given to patients for consent to be truly informed. (shrink)

BackgroundAn increasing number of studies utilize intracranial electrophysiology in human subjects to advance basic neuroscience knowledge. However, the use of neurosurgical patients as human research subjects raises important ethical considerations, particularly regarding informed consent and undue influence, as well as subjects’ motivations for participation. Yet a thorough empirical examination of these issues in a participant population has been lacking. The present study therefore aimed to empirically investigate ethical concerns regarding informed consent and voluntariness in Parkinson’s disease patients undergoing deep brain (...) stimulator (DBS) placement who participated in an intraoperative neuroscience study.MethodsTwo semi-structured 30-minute interviews were conducted preoperatively and postoperatively via telephone. Interviews assessed participants’ motivations for participation in the parent intraoperative study, recall of information presented during the informed consent process, and participants’ postoperative reflections on the research study.ResultsTwenty-two participants (mean age = 60.9) completed preoperative interviews at a mean of 7.8 days following informed consent and a mean of 5.2 days prior to DBS surgery. Twenty participants completed postoperative interviews at a mean of 5 weeks following surgery. All participants cited altruism or advancing medical science as “very important” or “important” in their decision to participate in the study. Only 22.7% (n = 5) correctly recalled one of the two risks of the study. Correct recall of other aspects of the informed consent was poor (36.4% for study purpose; 50.0% for study protocol; 36.4% for study benefits). All correctly understood that the study would not confer a direct therapeutic benefit to them.ConclusionEven though research coordinators were properly trained and the informed consent was administered according to protocol, participants demonstrated poor retention of study information. While intraoperative studies that aim to advance neuroscience knowledge represent a unique opportunity to gain fundamental scientific knowledge, improved standards for the informed consent process can help facilitate their ethical implementation. (shrink)

The US neutrino community gathered at the Workshop on the Intermediate Neutrino Program at Brookhaven National Laboratory February 4-6, 2015 to explore opportunities in neutrino physics over the next five to ten years. Scientists from particle, astroparticle and nuclear physics participated in the workshop. The workshop examined promising opportunities for neutrino physics in the intermediate term, including possible new small to mid-scale experiments, US contributions to large experiments, upgrades to existing experiments, R&D plans and theory. The workshop was organized into (...) two sets of parallel working group sessions, divided by physics topics and technology. Physics working groups covered topics on Sterile Neutrinos, Neutrino Mixing, Neutrino Interactions, Neutrino Properties and Astrophysical Neutrinos. Technology sessions were organized into Theory, Short-Baseline Accelerator Neutrinos, Reactor Neutrinos, Detector R&D and Source, Cyclotron and Meson Decay at Rest sessions.This report summarizes discussion and conclusions from the workshop. (shrink)

Science is made possible by the introduction of theoretical objects. Why this should be so has never been made clear. Indeed, it has never been made clear how theoretical objects are rightly to be understood, or in what ways they differ from more ordinary sorts of physical objects. What follows is a sketch of a new theory. In my view, this theory becomes explicit on the so-called “Copenhagen interpretation” of quantum mechanics. But it has implicitly characterized scientific development since the (...) revolution of the 16th and 17th centuries.How are theoretical objects rightly to be understood? I say that they are objects whose existence is postulated by a theory is alright as far as it goes, but it doesn’t go far enough. We also need to know what theories are. (shrink)

CHAPTER Heidegger and the Quantum Brain In any case the orientation to "I" and " consciousness" and re-presentation ...

The "Chinese Room" controversy between Searle and Churchland and Churchland over whether computers can think is subjected to Derridean "deconstruction." There is a hidden complicity underlying the debate which upholds traditional subject/object metaphysics, while deferring to future empirical science an account of the problematic semantic relation between brain syntax and the perceptible world. I show that an empirical solution along the lines hoped for is not scientifically conceivable at present. An alternative account is explored, based on the productivity of neural (...) nets, in which the semantic relation is found to be dynamical - a spontaneous, stochastic, self-organizing process. (shrink)

Quantum degrees of freedom greatly enrich nonlinear systems, which can support nonlocal control and superposition of states. Basing my discussion on Yasue’s quantum brain dynamics, I suggest that the Cartesian subject is a cybernetic process rather than a substance: I am nonlocal control and my meanings are cybernetic variables. Meanings as nonlocal attunements are not mechanically determined, thus is it concluded we have freedom to mean.

In lieu of an abstract, here is a brief excerpt of the content:Philosophy, Psychiatry, & Psychology 12.3 (2005) 229-234 [Access article in PDF] Nonlinear Dynamics at the Cutting Edge of Modernity: A Postmodern View Gordon Globus Keywords nonlinear dynamics, modernity, postmodernity, quantum brain theory, free will, self-organization, autopoiesis, autorhoesis Although nonlinear dynamical conceptu-alizations have been applied to psychia-try for over 20 years,1 they have not had significant impact on the field. Unfortunately Heinrichs' very thoughtful contribution to the discussion is (...) unlikely to move such disinterest. Pragmatically successful paradigms in the phase of Kuhnian "normal science" are highly resistant to change. There is no crisis that besets triumphalist biological psychiatry that might lead to clinical or scientific revolution. At the same time, as I suggest at the end of this commentary, the ideas of nonlinear dynamics may not be revolutionary enough, remaining staunchly within the framework of modernity.In what follows I discuss four issues related to Heinrichs' article. First, I try to enrich his presentation of nonlinear dynamics by bringing in the role of self-organization in the evolution of nonlinear dynamical brain systems and by making the nonlinear dynamics "tunable." Second, I discuss whether Heinrichs succeeds in avoiding the dualism of the biopsychosocial model that he criticizes. Third, I look at the issue of "free will," which Heinrichs would understandably like to avoid. Finally, I mention a new form of dynamics, namely thermofield dynamics, which I think is more promising than nonlinear dynamics. Self-Organizing Self-Tuning Nonlinear Dynamical Systems In the case of psychiatry, we are not considering nonlinear dynamical systems like the weather or an ecosystem, but the brain's neural networks in terms of nonlinear dynamics with all its chaos. There is a principle of such systems of neural networks that Heinrichs does not bring out, although it is extremely important for them. These systems are self-organizing under a Hamiltonian principle of "least energy." To use Hopfield and Tank's (1986) terms, nonlinear dynamical neural networks self-organize toward attractors that minimize the "computational energy" of the system, or for Smolensky (1988), self-organize toward "harmony," or for Globus (1995, 2003), in a Heideggerian vein, self-organize to maximize "belonging-together." In this elaborated framework, rational deliberation is one constraint among many on a self-organizing nonlinear dynamical process. [End Page 229]Heinrichs brings out beautifully the nonlinear dynamical way of thinking clinically. This is not the dynamics of mechanistic psychodynamics, which features psychological forces in vectorial conflict—id versus superego and their compromises—but a flowing evolution of states in which small changes in initial state may have large effects (nonlinearity) on the state trajectory. To live a life is often to feel surprise, which nonlinear dynamics with its chaotic regimes well portrays.But there is a way that classical Freud and nonlinear dynamical neural networks do come together—in the "economics," discharges and conservations of libidinal energy, expenditures and credits in Derrida's (1978) accounting. Heinrichs does not mention this similarity. The economic principles differ between Freud's late nineteenth-century thermodynamics and Heinrichs' late twentieth-century nonlinear dynamics, it is true, but it is all economics.Freud called this economic functioning the "pleasure principle" in which "libido" seeks to discharge its instinctual energy store, reducing the level of instinctual tension. This "primary process" proceeds to an attractor by the quickest, most direct way possible, whereas the "secondary process" defers reduction in instinctual tension, subjecting the primary process to thought. Self-organizing directly to the attractor is the primary process with which the secondary process interferes, introducing deferral.The economy of nonlinear dynamics pictures a "landscape," a variegated topography with peaks and valleys. Each point on the topography represents a state. Peak points are repellors—for example, states in which the phobic object is approached—and the lowest points of the valleys are attractors—for example, obsessions and compulsions. The path of occupied states self-organizes away from repellors and toward attractors. This topography is an energy landscape. Its dynamics spontaneously tends—"self-organizes"—toward least energy/high-constraint satisfaction. Freud's pleasure principle is just the Hamiltonian least energy... (shrink)

Freud considered dreams to be compositions of past waking experiences but this theory is untenable: (1) the process of compositing disparate memories into the seamless dream life is miraculous, and (2) authentically novel dream worlds are experienced. Dennett makes dreams into purely cognitive affairs, a matter of scripts, denying their perceptual appearing. I suggest that dreams are de novo constructions of actual perceptual worlds, not put together from memory scraps. Implications for waking perception are considered.

I said that the book is brilliant. This is not so much because of the conclusions eventually reached about the inadequacy of a purely naturalistic approach to mind. These conclusions are already familiar in the work of Donald Davidson and others. Rather, it is because of the accumulation of historical detail and insight on the basis of which these conclusions are reached. It is often said, for instance, that Kant is a watershed figure, in some sense synthesizing and then moving (...) beyond both empiricism and naturalism. Hatfield uses these terms. But he reinvests them with meaning and energy and in the process shows how radical Kant was in refocusing, by way of a sharp distinction between empirical and transcendental inquiries, the central questions of philosophy. (shrink)

If the brain has a level of quantum functioning that permits superposition of possibilities and nonlocal control of states, then new answers to the problem of the consciousness/brain relation become available. My discussion is based on Yasue and co-workers’ account of a quantum field theory of brain functioning, called ‘quantum brain dynamics’. In the framework developed each person can properly state: ‘I am nonlocal control and my meanings are control variables.’ Cognition is identified with a conjugate reality and perception is (...) where quantum cognition, quantum memory and the quantum re-presentation of quantum reality meet and make a conjugate match. A new problem arises with regard to the world, however, since on this interpretation the one world-in-common is relinquished in favour of multiple parallel world-thrownnesses. But since quantum physics remains to this day deeply uncommonsensical, we should not hope to provide quantum solutions in consciousness studies without overturning the deepest convictions of common sense. (shrink)

Bioconservative bioethicists (e.g., Kass, 2002, Human Dignity and Bioethics, 297–331, 2008; Sandel, 2007; Fukuyama, 2003) offer various kinds of philosophical arguments against cognitive enhancement—i.e., the use of medicine and technology to make ourselves “better than well” as opposed to merely treating pathologies. Two notable such bioconservative arguments appeal to ideas about (1) the value of achievement, and (2) authenticity. It is shown here that even if these arguments from achievement and authenticity cut ice against specifically pharmacologically driven cognitive enhancement, they (...) do not extend over to an increasingly viable form of technological cognitive enhancement – namely, cognitive enhancement via augmented reality. An important result is that AR-driven cognitive enhancement aimed at boosting performance in certain cognitive tasks might offer an interesting kind of “sweet spot” for proponents of cognitive enhancement, allowing us to pursue many of the goals of enhancement advocates without running into some of the most prominent objections from bioconservative philosophers. (shrink)

There is a very plausible principle linking abilities and possibilities: If S is able to Φ, then it is metaphysically possible that S Φ’s. Jack Spencer recently proposed a class of counterexamples to this principle involving the ability to know certain propositions. I renew an argument against these counterexamples based on the unknowability of Fitch propositions. In doing so, I provide a new argument for the unknowability of Fitch propositions and show that Spencer’s counterexamples are in tension with a principle (...) weaker than the one linking abilities and possibilities. (shrink)

Moral enhancement proposals struggle to be both plausible and ethically defensible while nevertheless interestingly distinct from both cognitive enhancement as well as (mere) moral education. Brian Earp (_Royal Institute of Philosophy Supplement_ 83:415–439, 12 ) suggests that a promising middle ground lies in focusing on the (suitably qualified) use of psychedelics as _adjuncts_ to moral development. But what would such an adjunctive use of psychedelics look like in practice? In this paper, I draw on literature from three areas where techniques (...) for moral development have been discussed: psychotherapy (e.g., Overholser 2010; Burns 1980) education (e.g., Uhl and Lütge, 2018), and AI-assisted enhancement (e.g., Lara and Deckers, _Neuroethics_ 13(3):275–287, 17 ) in order to propose more concrete ways in which to use psychedelics as adjuncts to moral development. It is shown that in each of these areas, we can see that _trusting_ relationships (e.g., Baier 1986; Hawley 2019) between the facilitator and the agent will very plausibly maximize the success of this type of moral enhancement. Finally, I appeal to literature on informed consent for use of psychedelics (e.g., Smith and Sisti, _Journal of Medical Ethics_, 22 ; Johnson et al., _The Journal of Psychopharmacology_ 22(6):603–20, 23 ) and on the therapeutic relationship in psychotherapy (e.g., Dryden and Reeves 2013; Horvath et al. 2011) to outline concrete suggestions for facilitating dimensions of trust most likely to maximize the benefits of (adjunctive) psychedelic moral enhancement. The result is a newly detailed practical proposal for how we might best facilitate moral enhancement by using drugs as adjuncts to moral development. (shrink)

It is often taken for granted that monitoring stands in some kind of tension with trusting (e.g., Hieronymi 2008; Wanderer and Townsend 2013; Nguyen forthcoming; McMyler 2011, Castelfranchi and Falcone 2000; Frey 1993; Dasgupta 1988, Litzky et al. 2006) — especially three-place trust (i.e., A trusts B to X), but sometimes also two-place trust (i.e., A trusts B, see, e.g., Baier 1986). Using a case study involving relationship breakdown, repair, and formation, I will argue there are some ways in which (...) monitoring can be conducive to two-place trust, and to instances of three-place trust that are likely to be repeated over time—especially when previously established two-place trust has broken down. The result, I hope, is not any kind of abandoning of the important idea that monitoring can undermine trust, but an appreciation of where the conflict between monitoring and trust doesn’t lie – one from which future work will hopefully be better positioned to illuminate where exactly the conflict is. (shrink)

ABSTRACT It is easy to think of consciousness as a medium, with two teams of philosophers disagreeing over whether the medium is transparent or translucent. G. E. Moore's “Refutation of Idealism” is still enlisted in defense of transparence, and Thomas Nagel's “What Is It Like to Be a Bat?” is still used to motivate translucency. I argue against both of these familiar interpretations of these articles and proceed to defend the very first response to Moore's article: James's insistence that consciousness, (...) construed as a transparent or translucent medium, just does not exist. Finally, and quite surprisingly, by refusing to treat consciousness as any sort of medium, James is able to account for how easy it is, and yet how difficult it is, to escape our insipid existence. (shrink)

I attempt to show that when someone is, E.G., Angry about something, The events or states that conjointly are causing him to be angry conform to a certain structure, And that from the causal structure underlying his anger it is possible to 'read out' what he is angry about. In this respect, And even in some of the details of the structure, My analysis of being angry about something resembles the belief-Want analysis of intentional action. The chief elements of the (...) causal structure I describe are a belief and an attitude so related in content as to constitute either a wish-Frustration (in the case of negative emotions) or a wish-Satisfaction (in the case of positive emotions). The analysis makes otiose, In those cases for which it is a correct analysis, The mysterious non-Causal relation between an emotion and its 'object' which is invoked by the majority of philosophers now writing on emotions. (shrink)

An emerging line of research in bioethics questions whether enhanced love is less significant or valuable than otherwise, where "enhanced love" generally refers to cases where drugs (e.g., oxytocin, etc.) are relied on to maintain romantic relationships. Separate from these debates is a recent body of literature on the philosophy and psychology of "Virtual Reality (VR) dating," where romantic relationships are developed and sustained in a way that is mediated by VR. Interestingly, these discussions have proceeded largely independently from each (...) other. This article considers whether and to what extent philosophical arguments leveled against the value of enhanced love in the pharmacological case extend to cases where loving relationships are technologically mediated via VR rather than pharmacologically mediated. It will be argued that, while some worries about the pharmacological case do not extend over in a way that will be particularly problematic for VR, two (of the four arguments considered) are more prima facie serious. I conclude by suggesting why even these stronger argument strategies are not insurmountable and, thus, that there is reason to be cautiously optimistic that VR-mediated love can largely withstand variations on the bioconservative critiques that target pharmacologically enhanced love. (shrink)

Robert M. Adams has written a fairly short book, but into it he has packed a lifetime of rigorous analytic thought, and, what is rarer, deep insight into the nature of things. The book expands and recasts Gifford Lectures that Adams delivered in 1999, as well as other lectures and papers, and though it addresses difficult issues, Adams's clear style, retaining the informality of lectures, considerably eases the task of the reader; and the book is not without an occasional touch (...) of humour, e.g. ‘As metaphysicians we may wish to assign a certain oomph to one side or the other in such lawgoverned relations; but it is not clear that the concept of oomph is at home in fundamental physics’ (p. 12).I cannot cover all the many and various topics in the book, but I shall endeavour in what follows to present a central thread of argument in it, the distinction between what is and what is in itself (the centrality of which is indicated by its presence in the book's title) and to show how this distinction leads to the theistic and idealist metaphysics to which the author is inclined. (shrink)

Plato: Symposium, translated by B. Jowett. Phaedo, translated by B. Jowett. Sophist, translated by B. Jowett.--Aristotle: De anima, translated by R. D. Hicks. Metaphysics (selections) translated by H. Tredennick. Nichomachean ethics (selections) translated by H. Rackham.--R. Descartes: Meditations, translated by E. S. Haldane and G. R. T. Ross.--G. Berkeley: Three dialogues between Hylas and Philonus.--D. Hume: Dialogues concerning natural religion.--I. Kant: Prolegomena to every future, translated by C. J. Friedrich. Metaphysical foundations of morals, translated by C. J. Friedrich.

This article explores the relationship between rhetoric and violence by running this pairing through a corresponding couplet: rhetoric and race. Arguing for a common substrate between these two pairs of terms—coloniality—this article proposes that rhetorics of "nonviolence" are better understood as rhetorics of anti-violence.

Reflecting Alan Robinson's fundamental contribution to computational logic, this book brings together seminal papers in inference, equality theories, and logic programming. It is an exceptional collection that ranges from surveys of major areas to new results in more specialized topics. Alan Robinson is currently the University Professor at Syracuse University. Jean-Louis Lassez is a Research Scientist at the IBM Thomas J. Watson Research Center. Gordon Plotkin is Professor of Computer Science at the University of Edinburgh. Contents: Inference. Subsumption, A (...) Sometimes Undervalued Procedure, Larry Wos, Ross Overbeek, and Ewing Lusk. The Markgraf Karl Refutation Procedure, Hans Jurgen Ohlbach and Jorg H. Siekmann. Modal Logic Should Say More than it Does, Melvin Fitting. Interactive Proof Presentation, W. W. Bledsoe. Intelligent Backtracking Revisited, Maurice Bruynooghe. A Science of Reasoning, Alan Bundy. Inductive Inference of Theories from Facts, Ehud Y. Shapiro. Equality. Solving Equations in Abstract Algebras: A Rule-based Survey of Unification, Jean-Pierre Jouannaud and Claude Kirchner. Disunification: A Survey, Hubert Comon. A Case Study of the Completion Procedure: Proving Ring Commutativity Problems, Deepak Kapur and Hantao Zhang. Computations in Regular Rewriting Systems I and II, Girard Huet and JeanJacques Levy. Unification and ML Type Reconstruction, Paris Kanellakis, Harry Mairson, and John Mitchell. Automatic Dimensional Analysis, Mitchell Wand. Logic Programming. Logic Programming Schemes and Their Implementations, Keith Clark. A Near-Horn Prolog for Compilation, Donald Loveland and David Reed. Unfold/Fold Transformations of Logic Programs, P. A. Gardner and J. C. Shepherdson. An Algebraic Representation of Logic Program Computations, Andrea Corradini and Ugo Montanari. Theory of Disjunctive Logic Programs, Jack Minker, Arcot Rajasekar, and Jorge Lobo. Bottom-Up Evaluation of Logic Programs, Jeffrey Naughton and Raghu Ramakrishnan. Absys, the First Logic Programming Language: A View of the Inevitability of Logic Programming, E. W. Elcock. (shrink)

There have been recent concerns about an “epidemic of loneliness” during the pandemic, given the pervasiveness of loneliness in the population and its harmful effects on health and well-being. Therefore, it is important to establish the correlates of loneliness. The purpose of the current study was to explore how loneliness relates to a construct termed mattering, which is the feeling of being important to other people. Mattering was assessed with multiple measures in the current study (e.g., mattering in general, fears (...) of not mattering, and mattering to peers). A sample of 172 female psychology undergraduate students aged 18–25 years completed self-report measures of general mattering, mattering to peers, anti-mattering, fear of not mattering, and state and trait loneliness. As predicted, lower levels of both general mattering and mattering to peers were associated with higher state loneliness. Higher feelings of anti-mattering (feelings of being invisible and insignificant to others) and fears of not mattering were associated with greater trait loneliness, as well as a reduced sense of mattering to friends. The findings illustrate that feeling as though one does not matter to others (i.e., feeling insignificant and unimportant) is associated with increased state and trait loneliness among young women. Implications are discussed for loneliness theory and how these results can enhance both clinical understanding and practice. (shrink)

Olympiodorus' Commentary on Plato's Phaedo I.3-6 has been the linchpin of the reconstructions of the supposed Orphic doctrine of original sin. While Olympiodorus links the Titans' dismemberment of Dionysus and anthropogony, he does not include any element of inherited guilt, either in his narration of the myth or in his interpretation. Moreover, his telling of the myth, which makes the anthropogony the sequel to the dismemberment of Dionysus, is an innovation made for the purposes of his own argument. Rather than (...) preserving in fossilized form a sacred myth more than a millennium old, Olympiodorus concocts an innovative tale of his own. (shrink)

On the first page of this very timely paper the author quotes Linda Gordon: This statement provides a theme for response to Jing-Bao Nie's arguments. In reading this paper, I found myself reminded of two of George Orwell's insights: (1) When governments use euphemisms they are usually up to no good: [e.g., the use of for abortion]. (2) Sexuality and the sexual act (I would add here reproduction—having children) can be a powerful tool of subversion and rebellion. One's sexuality (...) (and reproductive ability) can be the last line of defense against repression or authority. (shrink)

I. G. McFetridge; VII*—Propositions and Davidson's Account of Indirect Discourse, Proceedings of the Aristotelian Society, Volume 76, Issue 1, 1 June 1976, Page.